1L8B

Cocrystal Structure of the Messenger RNA 5' Cap-binding Protein (eIF4E) bound to 7-methylGpppG

Summary for 1L8B

Entry DOI	10.2210/pdb1l8b/pdb
Descriptor	EUKARYOTIC TRANSLATION INITIATION FACTOR 4E, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE (3 entities in total)
Functional Keywords	eukaryotic initiation factor 4e, eif4e, cap, 7-methylgpppg, rna binding protein
Biological source	Mus musculus (house mouse)
Total number of polymer chains	2
Total formula weight	45366.66
Authors	Niedzwiecka, A.,Marcotrigiano, J.,Stepinski, J.,Jankowska-Anyszka, M.,Wyslouch-Cieszynska, A.,Dadlez, M.,Gingras, A.-C.,Mak, P.,Darzynkiewicz, E.,Sonenberg, N. (deposition date: 2002-03-19, release date: 2002-06-12, Last modification date: 2024-02-14)
Primary citation	Niedzwiecka, A.,Marcotrigiano, J.,Stepinski, J.,Jankowska-Anyszka, M.,Wyslouch-Cieszynska, A.,Dadlez, M.,Gingras, A.C.,Mak, P.,Darzynkiewicz, E.,Sonenberg, N.,Burley, S.K.,Stolarski, R. Biophysical studies of eIF4E cap-binding protein: recognition of mRNA 5' cap structure and synthetic fragments of eIF4G and 4E-BP1 proteins. J.Mol.Biol., 319:615-635, 2002 Cited by PubMed: 12054859 DOI: 10.1016/S0022-2836(02)00328-5 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation