1L1M

SOLUTION STRUCTURE OF A DIMER OF LAC REPRESSOR DNA-BINDING DOMAIN COMPLEXED TO ITS NATURAL OPERATOR O1

1L1M の概要

• エントリーDOI: 10.2210/pdb1l1m/pdb
• NMR情報: BMRB: 5345
• 分子名称: 5'-D(*GP*AP*AP*TP*TP*GP*TP*GP*AP*GP*CP*GP*GP*AP*TP*AP*AP*CP*AP*AP*TP*TP*T)-3', 5'-D(*AP*AP*AP*TP*TP*GP*TP*TP*AP*TP*CP*CP*GP*CP*TP*CP*AP*CP*AP*AP*TP*TP*C)-3', Lactose operon repressor (3 entities in total)
• 機能のキーワード: transcription regulation, lac operon, lac repressor, natural lac operator, asymmetric dna-binding, hth, transcription regulator-dna complex, transcription regulator/dna
• 由来する生物種: Escherichia coli
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 27763.69

構造登録者

Kalodimos, C.G.,Bonvin, A.M.J.J.,Salinas, R.K.,Wechselberger, R.,Boelens, R.,Kaptein, R. (登録日: 2002-02-19, 公開日: 2002-06-26, 最終更新日: 2021-10-27)

• 主引用文献: Kalodimos, C.G.,Bonvin, A.M.,Salinas, R.K.,Wechselberger, R.,Boelens, R.,Kaptein, R.; Plasticity in protein-DNA recognition: lac repressor interacts with its natural operator 01 through alternative conformations of its DNA-binding domain.; EMBO J., 21:2866-2876, 2002; PubMed: 12065400; DOI: 10.1093/emboj/cdf318

実験手法

SOLUTION NMR