1KQU
Human phospholipase A2 complexed with a substrate anologue
Summary for 1KQU
Entry DOI | 10.2210/pdb1kqu/pdb |
Related | 1D4K 1D4L 1KQT |
Descriptor | Phospholipase A2, membrane associated, CALCIUM ION, 6-PHENYL-4(R)-(7-PHENYL-HEPTANOYLAMINO)-HEXANOIC ACID, ... (4 entities in total) |
Functional Keywords | phospholipase a2, inhibitor, hydrolase |
Biological source | Homo sapiens (human) |
Cellular location | Membrane; Peripheral membrane protein: P14555 |
Total number of polymer chains | 1 |
Total formula weight | 14420.70 |
Authors | Tyndall, J.D.,Martin, J.L. (deposition date: 2002-01-07, release date: 2003-11-11, Last modification date: 2023-08-16) |
Primary citation | Hansford, K.A.,Reid, R.C.,Clark, C.I.,Tyndall, J.D.,Whitehouse, M.W.,Guthrie, T.,McGeary, R.P.,Schafer, K.,Martin, J.L.,Fairlie, D.P. D-Tyrosine as a chiral precusor to potent inhibitors of human nonpancreatic secretory phospholipase A2 (IIa) with antiinflammatory activity. Chembiochem, 4:181-185, 2003 Cited by PubMed: 12616631DOI: 10.1002/cbic.200390029 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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