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1KI8

CRYSTAL STRUCTURE OF THYMIDINE KINASE FROM HERPES SIMPLEX VIRUS TYPE I COMPLEXED WITH 5-BROMOVINYLDEOXYURIDINE

Summary for 1KI8
Entry DOI10.2210/pdb1ki8/pdb
DescriptorTHYMIDINE KINASE, SULFATE ION, 5-BROMOVINYLDEOXYURIDINE, ... (4 entities in total)
Functional Keywordsphosphotransferase, thymidine kinase, viridae, ds-dna enveloped viruses, herpesviridae, alphaherpesvirinae, substrate analog, 5-bromovinyldeoxyuridine
Biological sourceHerpes simplex virus (type 1 / strain 17)
Total number of polymer chains2
Total formula weight72416.57
Authors
Champness, J.N.,Bennett, M.S.,Wien, F.,Visse, R.,Summers, W.C.,Sanderson, M.R. (deposition date: 1998-05-15, release date: 1998-12-02, Last modification date: 2024-02-14)
Primary citationChampness, J.N.,Bennett, M.S.,Wien, F.,Visse, R.,Summers, W.C.,Herdewijn, P.,de Clerq, E.,Ostrowski, T.,Jarvest, R.L.,Sanderson, M.R.
Exploring the active site of herpes simplex virus type-1 thymidine kinase by X-ray crystallography of complexes with aciclovir and other ligands.
Proteins, 32:350-361, 1998
Cited by
PubMed: 9715911
DOI: 10.1002/(SICI)1097-0134(19980815)32:3<350::AID-PROT10>3.0.CO;2-8
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.2 Å)
Structure validation

217705

数据于2024-03-27公开中

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