1K8T

Crystal structure of the adenylyl cyclase domain of anthrax edema factor (EF)

Summary for 1K8T

Entry DOI	10.2210/pdb1k8t/pdb
Descriptor	CALMODULIN-SENSITIVE ADENYLATE CYCLASE, SULFATE ION, NICKEL (II) ION, ... (4 entities in total)
Functional Keywords	edema factor, adenylyl cyclase, anthrax, calmodulin, toxin, lyase
Biological source	Bacillus anthracis
Cellular location	Secreted: P40136
Total number of polymer chains	1
Total formula weight	59253.55
Authors	Drum, C.L.,Yan, S.-Z.,Bard, J.,Shen, Y.-Q.,Lu, D.,Soelaiman, S.,Grabarek, Z.,Bohm, A.,Tang, W.-J. (deposition date: 2001-10-25, release date: 2002-01-23, Last modification date: 2024-04-03)
Primary citation	Drum, C.L.,Yan, S.-Z.,Bard, J.,Shen, Y.-Q.,Lu, D.,Soelaiman, S.,Grabarek, Z.,Bohm, A.,Tang, W.-J. Structural basis for the activation of anthrax adenylyl cyclase exotoxin by calmodulin Nature, 415:396-402, 2002 Cited by PubMed: 11807546 DOI: 10.1038/415396a PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation