1K1G

STRUCTURAL BASIS FOR RECOGNITION OF THE INTRON BRANCH SITE RNA BY SPLICING FACTOR 1

Summary for 1K1G

• Entry DOI: 10.2210/pdb1k1g/pdb
• Descriptor: 5'-R(*UP*AP*UP*AP*CP*UP*AP*AP*CP*AP*A)-3', SF1-Bo isoform (2 entities in total)
• Functional Keywords: splicing, branch point sequence, protein/rna recognition, complex e, kh domain, qua2 homology, star proteins, gene regulation-rna complex, gene regulation/rna
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus: Q15637
• Total number of polymer chains: 2
• Total formula weight: 18162.03

Authors

Liu, Z.,Luyten, I.,Bottomley, M.J.,Messias, A.C.,Houngninou-Molango, S.,Sprangers, R.,Zanier, K.,Kramer, A.,Sattler, M. (deposition date: 2001-09-25, release date: 2001-11-07, Last modification date: 2022-02-23)

• Primary citation: Liu, Z.,Luyten, I.,Bottomley, M.J.,Messias, A.C.,Houngninou-Molango, S.,Sprangers, R.,Zanier, K.,Kramer, A.,Sattler, M.; Structural basis for recognition of the intron branch site RNA by splicing factor 1.; Science, 294:1098-1102, 2001; PubMed: 11691992; DOI: 10.1126/science.1064719

Experimental method

SOLUTION NMR