1K1G

STRUCTURAL BASIS FOR RECOGNITION OF THE INTRON BRANCH SITE RNA BY SPLICING FACTOR 1

1K1G の概要

• エントリーDOI: 10.2210/pdb1k1g/pdb
• 分子名称: 5'-R(*UP*AP*UP*AP*CP*UP*AP*AP*CP*AP*A)-3', SF1-Bo isoform (2 entities in total)
• 機能のキーワード: splicing, branch point sequence, protein/rna recognition, complex e, kh domain, qua2 homology, star proteins, gene regulation-rna complex, gene regulation/rna
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Nucleus: Q15637
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 18162.03

構造登録者

Liu, Z.,Luyten, I.,Bottomley, M.J.,Messias, A.C.,Houngninou-Molango, S.,Sprangers, R.,Zanier, K.,Kramer, A.,Sattler, M. (登録日: 2001-09-25, 公開日: 2001-11-07, 最終更新日: 2022-02-23)

• 主引用文献: Liu, Z.,Luyten, I.,Bottomley, M.J.,Messias, A.C.,Houngninou-Molango, S.,Sprangers, R.,Zanier, K.,Kramer, A.,Sattler, M.; Structural basis for recognition of the intron branch site RNA by splicing factor 1.; Science, 294:1098-1102, 2001; PubMed: 11691992; DOI: 10.1126/science.1064719

実験手法

SOLUTION NMR