1J04

Structural mechanism of enzyme mistargeting in hereditary kidney stone disease in vitro

1J04 の概要

• エントリーDOI: 10.2210/pdb1j04/pdb
• 関連するPDBエントリー: 1H0C
• 分子名称: alanine--glyoxylate aminotransferase, (AMINOOXY)ACETIC ACID, GLYCEROL, ... (4 entities in total)
• 機能のキーワード: transferase, aminotransferase, pyridoxal phosphate
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 44126.82

構造登録者

Zhang, X.,Djordjevic, S.,Bartlam, M.,Ye, S.,Rao, Z.,Danpure, C.J. (登録日: 2002-10-30, 公開日: 2003-11-11, 最終更新日: 2023-11-15)

• 主引用文献: Djordjevic, S.,Zhang, X.,Bartlam, M.,Ye, S.,Rao, Z.,Danpure, C.J.; Structural implications of a G170R mutation of alanine:glyoxylate aminotransferase that is associated with peroxisome-to-mitochondrion mistargeting.; Acta Crystallogr.,Sect.F, 66:233-236, 2010; PubMed: 20208150; DOI: 10.1107/S1744309109054645

実験手法

X-RAY DIFFRACTION (2.6 Å)