1IYO

Toho-1 beta-Lactamase In Complex With Cefotaxime

Summary for 1IYO

• Entry DOI: 10.2210/pdb1iyo/pdb
• Related: 1IYP 1IYQ
• Descriptor: Toho-1 beta-lactamase, SULFATE ION, CEFOTAXIME, C3' cleaved, open, bound form, ... (4 entities in total)
• Functional Keywords: extended-spectrum, esbl, beta-lactamase, acyl-enzyme, cefotaxime, complex, hydrolase
• Biological source: Escherichia coli
• Total number of polymer chains: 1
• Total formula weight: 28889.55

Authors

Shimamura, T.,Ibuka, A.,Fushinobu, S.,Wakagi, T.,Ishiguro, M.,Ishii, Y.,Matsuzawa, H. (deposition date: 2002-09-04, release date: 2002-12-11, Last modification date: 2023-12-27)

• Primary citation: Shimamura, T.,Ibuka, A.,Fushinobu, S.,Wakagi, T.,Ishiguro, M.,Ishii, Y.,Matsuzawa, H.; Acyl-intermediate Structures of the Extended-spectrum Class A beta -Lactamase, Toho-1, in Complex with Cefotaxime, Cephalothin, and Benzylpenicillin.; J.Biol.Chem., 277:46601-46608, 2002; PubMed: 12221102; DOI: 10.1074/jbc.M207884200

Experimental method

X-RAY DIFFRACTION (1.8 Å)