1IEG

CRYSTAL STRUCTURE OF THE CATALYTIC SITE MUTANT S134A/H157A OF THE HUMAN CYTOMEGALOVIRUS PROTEASE

Summary for 1IEG

• Entry DOI: 10.2210/pdb1ieg/pdb
• Related: 1ID4 1IEC 1IED 1IEF 1WPO 2WPO
• Descriptor: CAPSID PROTEIN P40: ASSEMBLIN PROTEASE (2 entities in total)
• Functional Keywords: coat protein, hydrolase, serine protease, catalytic triad, viral protease
• Biological source: Human herpesvirus 5
• Cellular location: Protease precursor: Host cytoplasm. Assemblin: Host nucleus. Assembly protein: Host nucleus: P16753
• Total number of polymer chains: 2
• Total formula weight: 56094.96

Authors

Khayat, R.,Batra, R.,Massariol, M.J.,Lagace, L.,Tong, L. (deposition date: 2001-04-09, release date: 2001-06-06, Last modification date: 2024-02-07)

• Primary citation: Khayat, R.,Batra, R.,Massariol, M.J.,Lagace, L.,Tong, L.; Investigating the role of histidine 157 in the catalytic activity of human cytomegalovirus protease.; Biochemistry, 40:6344-6351, 2001; PubMed: 11371196; DOI: 10.1021/bi010158b

Experimental method

X-RAY DIFFRACTION (2 Å)