1IAQ

C-H-RAS P21 PROTEIN MUTANT WITH THR 35 REPLACED BY SER (T35S) COMPLEXED WITH GUANOSINE-5'-[B,G-IMIDO] TRIPHOSPHATE

Summary for 1IAQ

Entry DOI	10.2210/pdb1iaq/pdb
Descriptor	TRANSFORMING PROTEIN P21/H-RAS-1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER (3 entities in total)
Functional Keywords	gtp-binding, proto-oncogene, signaling protein
Biological source	Homo sapiens (human)
Cellular location	Cell membrane. Isoform 2: Nucleus: P01112
Total number of polymer chains	3
Total formula weight	58223.00
Authors	Spoerner, M.,Herrmann, C.,Vetter, I.R.,Kalbitzer, H.R.,Wittinghofer, A. (deposition date: 2001-03-23, release date: 2001-06-06, Last modification date: 2023-10-25)
Primary citation	Spoerner, M.,Herrmann, C.,Vetter, I.R.,Kalbitzer, H.R.,Wittinghofer, A. Dynamic properties of the Ras switch I region and its importance for binding to effectors. Proc.Natl.Acad.Sci.USA, 98:4944-4949, 2001 Cited by PubMed: 11320243 DOI: 10.1073/pnas.081441398 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation