1HNI

STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN A COMPLEX WITH THE NONNUCLEOSIDE INHIBITOR ALPHA-APA R 95845 AT 2.8 ANGSTROMS RESOLUTION

Summary for 1HNI

• Entry DOI: 10.2210/pdb1hni/pdb
• Descriptor: HIV-1 REVERSE TRANSCRIPTASE (SUBUNIT P66), HIV-1 REVERSE TRANSCRIPTASE (SUBUNIT P51), (2-ACETYL-5-METHYLANILINO)(2,6-DIBROMOPHENYL)ACETAMIDE (3 entities in total)
• Functional Keywords: nucleotidyltransferase
• Biological source: Human immunodeficiency virus 1; More
• Cellular location: Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P03366 P03367
• Total number of polymer chains: 2
• Total formula weight: 114624.06

Authors

Ding, J.,Das, K.,Arnold, E. (deposition date: 1995-02-28, release date: 1995-06-03, Last modification date: 2024-02-07)

• Primary citation: Ding, J.,Das, K.,Tantillo, C.,Zhang, W.,Clark Jr., A.D.,Jessen, S.,Lu, X.,Hsiou, Y.,Jacobo-Molina, A.,Andries, K.,Pauwels, R.,Moereels, H.,Koymans, L.,Janssen, P.A.J.,Smith Jr., R.H.,Koepke, M.K.,Michejda, C.J.,Hughes, S.H.,Arnold, E.; Structure of HIV-1 reverse transcriptase in a complex with the non-nucleoside inhibitor alpha-APA R 95845 at 2.8 A resolution.; Structure, 3:365-379, 1995; PubMed: 7542140; DOI: 10.1016/S0969-2126(01)00168-X

Experimental method

X-RAY DIFFRACTION (2.8 Å)