1HFD
HUMAN COMPLEMENT FACTOR D IN A P21 CRYSTAL FORM
Summary for 1HFD
| Entry DOI | 10.2210/pdb1hfd/pdb |
| Descriptor | COMPLEMENT FACTOR D (2 entities in total) |
| Functional Keywords | serine protease, hydrolase, complement, factor d, catalytic triad, self-regulation |
| Biological source | Homo sapiens (human) |
| Cellular location | Secreted: P00746 |
| Total number of polymer chains | 1 |
| Total formula weight | 24438.81 |
| Authors | Jing, H.,Babu, Y.S.,Moore, D.,Kilpatrick, J.M.,Liu, X.-Y.,Volanakis, J.E.,Narayana, S.V.L. (deposition date: 1998-06-18, release date: 1999-06-22, Last modification date: 2023-08-09) |
| Primary citation | Jing, H.,Babu, Y.S.,Moore, D.,Kilpatrick, J.M.,Liu, X.Y.,Volanakis, J.E.,Narayana, S.V. Structures of native and complexed complement factor D: implications of the atypical His57 conformation and self-inhibitory loop in the regulation of specific serine protease activity. J.Mol.Biol., 282:1061-1081, 1998 Cited by PubMed: 9753554DOI: 10.1006/jmbi.1998.2089 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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