1HCQ
THE CRYSTAL STRUCTURE OF THE ESTROGEN RECEPTOR DNA-BINDING DOMAIN BOUND TO DNA: HOW RECEPTORS DISCRIMINATE BETWEEN THEIR RESPONSE ELEMENTS
Summary for 1HCQ
Entry DOI | 10.2210/pdb1hcq/pdb |
Descriptor | DNA (5'-D(*CP*CP*AP*GP*GP*TP*CP*AP*CP*AP*GP*TP*GP*AP*CP*CP*T P*G)-3'), DNA (5'-D(*CP*CP*AP*GP*GP*TP*CP*AP*CP*TP*GP*TP*GP*AP*CP*CP*T P*G)-3'), PROTEIN (ESTROGEN RECEPTOR), ... (5 entities in total) |
Functional Keywords | protein-dna complex, complexed with drug, transcription-dna complex, transcription/dna |
Biological source | Homo sapiens (human) |
Cellular location | Isoform 1: Nucleus. Isoform 3: Nucleus: P03372 |
Total number of polymer chains | 8 |
Total formula weight | 61356.59 |
Authors | Schwabe, J.W.R.,Chapman, L.,Finch, J.T.,Rhodes, D. (deposition date: 1995-01-04, release date: 1995-11-23, Last modification date: 2022-12-21) |
Primary citation | Schwabe, J.W.,Chapman, L.,Finch, J.T.,Rhodes, D. The crystal structure of the estrogen receptor DNA-binding domain bound to DNA: how receptors discriminate between their response elements. Cell(Cambridge,Mass.), 75:567-578, 1993 Cited by PubMed: 8221895DOI: 10.1016/0092-8674(93)90390-C PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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