1H6F

Human TBX3, a transcription factor responsible for ulnar-mammary syndrome, bound to a palindromic DNA site

Summary for 1H6F

DescriptorT-BOX TRANSCRIPTION FACTOR TBX3, 5'-D(*TP*AP*AP*TP*TP*TP*CP*AP*CP*AP*CP*CP*TP* AP*GP*GP*TP*GP*TP*GP*AP*AP*AP*T)-3', MAGNESIUM ION, ... (4 entities in total)
Functional Keywordstranscription factor, tbx3, t-box transcription factor, ulnar-mammary syndrome, holt-oram-syndrome, ig-fold, dna-binding, repressor, nuclear protein, developmental protein
Biological sourceHOMO SAPIENS (HUMAN)
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Cellular locationNucleus  O15119
Total number of polymer chains4
Total molecular weight60156.62
Authors
Coll, M.,Muller, C.W. (deposition date: 2001-06-13, release date: 2002-04-19, Last modification date: 2018-03-28)
Primary citation
Coll, M.,Seidman, J.G.,Muller, C.W.
Structure of the DNA-Bound T-Box Domain of Human Tbx3, a Transcription Factor Responsible for Ulnar- Mammary Syndrome
Structure, 10:343-, 2002
PubMed: 12005433 (PDB entries with the same primary citation)
DOI: 10.1016/S0969-2126(02)00722-0
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.7 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliers1101.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report