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1H0W

Human cyclin dependent protein kinase 2 in complex with the inhibitor 2-Amino-6-[cyclohex-3-enyl]methoxypurine

Summary for 1H0W
Entry DOI10.2210/pdb1h0w/pdb
Related1AQ1 1B38 1B39 1BUH 1CKP 1DI8 1DM2 1E1V 1E1X 1E9H 1F5Q 1FIN 1FQ1 1FVT 1FVV 1G5S 1GIH 1GII 1GIJ 1GY3 1GZ8 1H00 1H01 1H06 1H07 1H08 1H0U 1H0V 1HCK 1HCL 1JST 1JSU 1JSV 1JVP 1QMZ
DescriptorCELL DIVISION PROTEIN KINASE 2, 1-AMINO-6-CYCLOHEX-3-ENYLMETHYLOXYPURINE (3 entities in total)
Functional Keywordstransferase, protein kinase, cell cycle, phosphorylation, cell division, mitosis, inhibition
Biological sourceHOMO SAPIENS (HUMAN)
Total number of polymer chains1
Total formula weight34222.80
Authors
Primary citationGibson, A.E.,Arris, C.E.,Bentley, J.,Boyle, F.T.,Curtin, N.J.,Davies, T.G.,Endicott, J.A.,Golding, B.T.,Grant, S.,Griffin, R.J.,Jewsbury, P.,Johnson, L.N.,Mesguiche, V.,Newell, D.R.,Noble, M.E.M.,Tucker, J.A.,Whitfield, H.J.
Probing the ATP Ribose-Binding Domain of Cyclin-Dependent Kinases 1 and 2 with O(6)-Substituted Guanine Derivatives
J.Med.Chem., 45:3381-, 2002
Cited by
PubMed: 12139449
DOI: 10.1021/JM020056Z
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.1 Å)
Structure validation

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