1GVU

Endothiapepsin complex with H189

Summary for 1GVU

• Entry DOI: 10.2210/pdb1gvu/pdb
• Related: 1E5O 1E80 1E81 1E82 1EED 1ENT 1EPL 1EPM 1EPN 1EPO 1EPP 1EPQ 1EPR 1ER8 1GKT 1GVT 1GVV 1GVW 1GVX 2ER0 2ER6 2ER7 2ER9 3ER3 3ER5 4APE 4ER1 4ER2 4ER4 5ER1 5ER2
• Related PRD ID: PRD_000430
• Descriptor: ENDOTHIAPEPSIN, INHIBITOR, H189, SULFATE ION, ... (4 entities in total)
• Functional Keywords: hydrolase, aspartic proteinase mechanism, atomic resolution, z tetrahedral intermediate, anisotropic refinement, aspartyl p, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: ENDOTHIA PARASITICA (CHESTNUT BLIGHT FUNGUS); More
• Total number of polymer chains: 2
• Total formula weight: 35260.50

Authors

Coates, L.,Erskine, P.T.,Crump, M.P.,Wood, S.P.,Cooper, J.B. (deposition date: 2002-02-27, release date: 2002-07-04, Last modification date: 2023-11-15)

• Primary citation: Coates, L.,Erskine, P.T.,Crump, M.P.,Wood, S.P.,Cooper, J.B.; Five Atomic Resolution Structures of Endothiapepsin Inhibitor Complexes: Implications for the Aspartic Proteinase Mechanism; J.Mol.Biol., 318:1405-, 2002; PubMed: 12083527; DOI: 10.1016/S0022-2836(02)00197-3

Experimental method

X-RAY DIFFRACTION (0.94 Å)