1GIS

A TRICHOSANTHIN(TCS) MUTANT(E85Q) COMPLEX STRUCTURE WITH 2'-DEOXY-ADENOSIN-5'-MONOPHOSPHATE

Summary for 1GIS

• Entry DOI: 10.2210/pdb1gis/pdb
• Related: 1GIU
• Descriptor: RIBOSOME-INACTIVATING PROTEIN ALPHA-TRICHOSANTHIN, 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE (3 entities in total)
• Functional Keywords: protein-sub complex, trichosanthin, tcs, hydrolase
• Biological source: Trichosanthes kirilowii
• Total number of polymer chains: 1
• Total formula weight: 27628.20

Authors

Guo, Q.,Liu, Y.,Dong, Y.,Rao, Z. (deposition date: 2001-03-15, release date: 2003-06-03, Last modification date: 2023-12-27)

• Primary citation: Guo, Q.,Zhou, W.,Too, H.M.,Li, J.,Liu, Y.,Bartlam, M.,Dong, Y.,Wong, K.B.,Shaw, P.C.,Rao, Z.; Substrate binding and catalysis in trichosanthin occur in different sites as revealed by the complex structures of several E85 mutants.; Protein Eng., 16:391-396, 2003; PubMed: 12874371; DOI: 10.1093/protein/gzg056

Experimental method

X-RAY DIFFRACTION (1.7 Å)