1FQE

CRYSTAL STRUCTURES OF MUTANT (K206A) THAT ABOLISH THE DILYSINE INTERACTION IN THE N-LOBE OF HUMAN TRANSFERRIN

1FQE の概要

• エントリーDOI: 10.2210/pdb1fqe/pdb
• 関連するPDBエントリー: 1A8E 1FQF
• 分子名称: SEROTRANSFERRIN, FE (III) ION, CARBONATE ION, ... (5 entities in total)
• 機能のキーワード: iron transport, transferrin, n-lobe, iron-release, dilysine interaction, metal transport
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Secreted: P02787
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 36701.51

構造登録者

Nurizzo, D.,Baker, H.M.,Baker, E.N. (登録日: 2000-09-04, 公開日: 2001-05-16, 最終更新日: 2021-11-03)

• 主引用文献: Nurizzo, D.,Baker, H.M.,He, Q.Y.,MacGillivray, R.T.,Mason, A.B.,Woodworth, R.C.,Baker, E.N.; Crystal structures and iron release properties of mutants (K206A and K296A) that abolish the dilysine interaction in the N-lobe of human transferrin.; Biochemistry, 40:1616-1623, 2001; PubMed: 11327820; DOI: 10.1021/bi002050m

実験手法

X-RAY DIFFRACTION (1.8 Å)