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1FE8

CRYSTAL STRUCTURE OF THE VON WILLEBRAND FACTOR A3 DOMAIN IN COMPLEX WITH A FAB FRAGMENT OF IGG RU5 THAT INHIBITS COLLAGEN BINDING

Summary for 1FE8
Entry DOI10.2210/pdb1fe8/pdb
Related1AO3 1ATZ
DescriptorVON WILLEBRAND FACTOR, IMMUNOGLOBULIN IGG RU5, alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
Functional Keywordscollagen binding, conformational changes, epitope, von willebrand factor a-type domain, immune system
Biological sourceHomo sapiens (human)
More
Total number of polymer chains9
Total formula weight201594.32
Authors
Bouma, B.,Huizinga, E.G.,Schiphorst, M.E.,Sixma, J.J.,Kroon, J.,Gros, P. (deposition date: 2000-07-21, release date: 2001-04-04, Last modification date: 2020-07-29)
Primary citationRomijn, R.A.,Bouma, B.,Wuyster, W.,Gros, P.,Kroon, J.,Sixma, J.J.,Huizinga, E.G.
Identification of the collagen-binding site of the von Willebrand factor A3-domain.
J.Biol.Chem., 276:9985-9991, 2001
Cited by
PubMed: 11098050
DOI: 10.1074/jbc.M006548200
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.03 Å)
Structure validation

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