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1F3F

STRUCTURE OF THE H122G NUCLEOSIDE DIPHOSPHATE KINASE / D4T-TRIPHOSPHATE.MG COMPLEX

Summary for 1F3F
Entry DOI10.2210/pdb1f3f/pdb
DescriptorPROTEIN (NUCLEOSIDE DIPHOSPHATE KINASE), MAGNESIUM ION, 2',3'-DEHYDRO-2',3'-DEOXY-THYMIDINE 5'-TRIPHOSPHATE, ... (6 entities in total)
Functional Keywordsnucleoside diphosphate kinase, anti-hiv nucleoside analogue, phosphorylation, ch...o bond, transferase
Biological sourceDictyostelium discoideum
Cellular locationCytoplasm: P22887
Total number of polymer chains3
Total formula weight52150.24
Authors
Meyer, P.,Schneider, B.,Sarfati, S.,Deville-Bonne, D.,Guerreiro, C.,Boretto, J.,Janin, J.,Veron, M.,Canard, B. (deposition date: 2000-06-02, release date: 2000-09-13, Last modification date: 2024-02-07)
Primary citationMeyer, P.,Schneider, B.,Sarfati, S.,Deville-Bonne, D.,Guerreiro, C.,Boretto, J.,Janin, J.,Veron, M.,Canard, B.
Structural basis for activation of alpha-boranophosphate nucleotide analogues targeting drug-resistant reverse transcriptase.
EMBO J., 19:3520-3529, 2000
Cited by
PubMed: 10899107
DOI: 10.1093/emboj/19.14.3520
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.85 Å)
Structure validation

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