1EVG

CRYSTAL STRUCTURE ANALYSIS OF CYS167 MUTANT OF ESCHERICHIA COLI WITH UNMODIFIED CATALYTIC CYSTEINE

Summary for 1EVG

Entry DOI	10.2210/pdb1evg/pdb
Related	1EV5 1EV8 1EVF
Descriptor	THYMIDYLATE SYNTHASE, SULFATE ION (3 entities in total)
Functional Keywords	thr167 e. coli thymidylate synthase with unmodified catalytic cysteine, transferase
Biological source	Escherichia coli
Cellular location	Cytoplasm : P0A884
Total number of polymer chains	1
Total formula weight	31014.11
Authors	Phan, J.,Mahdavian, E.,Nivens, M.C.,Minor, W.,Berger, S.,Spencer, H.T.,Dunlap, R.B.,Lebioda, L. (deposition date: 2000-04-19, release date: 2000-05-03, Last modification date: 2022-04-13)
Primary citation	Phan, J.,Mahdavian, E.,Nivens, M.C.,Minor, W.,Berger, S.,Spencer, H.T.,Dunlap, R.B.,Lebioda, L. Catalytic cysteine of thymidylate synthase is activated upon substrate binding. Biochemistry, 39:6969-6978, 2000 Cited by PubMed: 10841779 DOI: 10.1021/bi000367g PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation