1DZ5

The NMR structure of the 38KDa U1A protein-PIE RNA complex reveals the basis of cooperativity in regulation of polyadenylation by human U1A protein

Summary for 1DZ5

Related1AUD 1FHT 1URN
DescriptorU1 SMALL NUCLEAR RIBONUCLEOPROTEIN A, PIE, RNA (5'-R(*GP*AP*GP*AP*CP*AP*UP*UP*GP*CP*AP*CP*CP* CP*GP*GP*AP*GP*UP*CP*UP*C)-3') (2 entities in total)
Functional Keywordsribonucleoprotein-rna complex, polyadenylation, protein protein interaction, rna protein interaction, ribonucleoprotein/rna
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationNucleus P09012
Total number of polymer chains4
Total molecular weight37293.65
Authors
Varani, L.,Gunderson, S.I.,Mattaj, I.W.,Kay, L.E.,Neuhaus, D.,Varani, G. (deposition date: 2000-02-16, release date: 2000-03-29, Last modification date: 2013-05-15)
Primary citation
Varani, L.,Gunderson, S.I.,Mattaj, I.W.,Kay, L.E.,Neuhaus, D.,Varani, G.
The NMR Structure of the 38kDa U1A Protein-Pie RNA Complex Reveals the Basis of Cooperativity in Regulation of Polyadenylation by Human U1A Protein
Nat.Struct.Biol., 7:329-, 2000
PubMed: 10742179 (PDB entries with the same primary citation)
DOI: 10.1038/74101
MImport into Mendeley
Experimental method
SOLUTION NMR
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Structure validation

ClashscoreRamachandran outliersSidechain outliersRNA backbone365.1%16.4%0.06MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures
Download full validation report