1DYI

ISOMORPHOUS CRYSTAL STRUCTURES OF ESCHERICHIA COLI DIHYDROFOLATE REDUCTASE COMPLEXED WITH FOLATE, 5-DEAZAFOLATE AND 5,10-DIDEAZATETRAHYDROFOLATE: MECHANISTIC IMPLICATIONS

1DYI の概要

• エントリーDOI: 10.2210/pdb1dyi/pdb
• 分子名称: DIHYDROFOLATE REDUCTASE, CHLORIDE ION, FOLIC ACID, ... (5 entities in total)
• 機能のキーワード: oxidoreductase
• 由来する生物種: Escherichia coli
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 37034.43

構造登録者

Reyes, V.M.,Kraut, J. (登録日: 1994-10-26, 公開日: 1995-06-03, 最終更新日: 2024-02-07)

• 主引用文献: Reyes, V.M.,Sawaya, M.R.,Brown, K.A.,Kraut, J.; Isomorphous crystal structures of Escherichia coli dihydrofolate reductase complexed with folate, 5-deazafolate, and 5,10-dideazatetrahydrofolate: mechanistic implications.; Biochemistry, 34:2710-2723, 1995; PubMed: 7873554; DOI: 10.1021/bi00008a039

実験手法

X-RAY DIFFRACTION (1.9 Å)