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1DRB

CRYSTAL STRUCTURE OF UNLIGANDED ESCHERICHIA COLI DIHYDROFOLATE REDUCTASE. LIGAND-INDUCED CONFORMATIONAL CHANGES AND COOPERATIVITY IN BINDING

Summary for 1DRB
Entry DOI10.2210/pdb1drb/pdb
DescriptorDIHYDROFOLATE REDUCTASE, CHLORIDE ION, METHOTREXATE, ... (6 entities in total)
Functional Keywordsoxidoreductase
Biological sourceEscherichia coli
Total number of polymer chains2
Total formula weight37128.76
Authors
David, C.,Kraut, J. (deposition date: 1991-11-06, release date: 1994-01-31, Last modification date: 2024-02-07)
Primary citationBystroff, C.,Kraut, J.
Crystal structure of unliganded Escherichia coli dihydrofolate reductase. Ligand-induced conformational changes and cooperativity in binding.
Biochemistry, 30:2227-2239, 1991
Cited by
PubMed: 1998681
DOI: 10.1021/bi00222a028
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.96 Å)
Structure validation

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