1DO8

CRYSTAL STRUCTURE OF A CLOSED FORM OF HUMAN MITOCHONDRIAL NAD(P)+-DEPENDENT MALIC ENZYME

Summary for 1DO8

Entry DOI	10.2210/pdb1do8/pdb
Related	1qr6
Descriptor	MALIC ENZYME, OXALATE ION, MANGANESE (II) ION, ... (5 entities in total)
Functional Keywords	oxidative decarboxylase, four domains: one with rossmann fold, one with parallel alpha-beta fold, one mostly helical, and one mostly extended, oxidoreductase
Biological source	Homo sapiens (human)
Cellular location	Mitochondrion matrix: P23368
Total number of polymer chains	4
Total formula weight	261451.90
Authors	Yang, Z.,Floyd, D.L.,Loeber, G.,Tong, L. (deposition date: 1999-12-19, release date: 2000-03-06, Last modification date: 2024-03-13)
Primary citation	Yang, Z.,Floyd, D.L.,Loeber, G.,Tong, L. Structure of a closed form of human malic enzyme and implications for catalytic mechanism. Nat.Struct.Biol., 7:251-257, 2000 Cited by PubMed: 10700286 DOI: 10.1038/73378 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation