1DLB

HELICAL INTERACTIONS IN THE HIV-1 GP41 CORE REVEALS STRUCTURAL BASIS FOR THE INHIBITORY ACTIVITY OF GP41 PEPTIDES

Summary for 1DLB

• Entry DOI: 10.2210/pdb1dlb/pdb
• Descriptor: HIV-1 ENVELOPE GLYCOPROTEIN GP41 (2 entities in total)
• Functional Keywords: gp41, hiv-1, membrane fusion, hiv-1 inhibition, virus/viral protein, viral protein
• Biological source: Human immunodeficiency virus 1; More
• Cellular location: Transmembrane protein gp41: Virion membrane; Single-pass type I membrane protein. Surface protein gp120: Virion membrane; Peripheral membrane protein: P04578
• Total number of polymer chains: 1
• Total formula weight: 7864.78

Authors

Shu, W.,Liu, J.,Ji, H.,Rading, L.,Jiang, S.,Lu, M. (deposition date: 1999-12-09, release date: 1999-12-15, Last modification date: 2024-02-07)

• Primary citation: Shu, W.,Liu, J.,Ji, H.,Radigen, L.,Jiang, S.,Lu, M.; Helical interactions in the HIV-1 gp41 core reveal structural basis for the inhibitory activity of gp41 peptides.; Biochemistry, 39:1634-1642, 2000; PubMed: 10677212; DOI: 10.1021/bi9921687

Experimental method

X-RAY DIFFRACTION (2 Å)