Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

1CVW

Crystal structure of active site-inhibited human coagulation factor VIIA (DES-GLA)

Summary for 1CVW
Entry DOI10.2210/pdb1cvw/pdb
Related1DAN
Related PRD IDPRD_000287
DescriptorCOAGULATION FACTOR VIIA (LIGHT CHAIN) (DES-GLA), COAGULATION FACTOR VIIA (HEAVY CHAIN) (DES-GLA), N-{[5-(dimethylamino)naphthalen-1-yl]sulfonyl}-L-alpha-glutamyl-N-[(2S,3S)-6-carbamimidamido-1-chloro-2-hydroxyhexan-3-yl]glycinamide, ... (5 entities in total)
Functional Keywordsblood coagulation, factor viia, serine protease, egf, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceHomo sapiens (human)
More
Cellular locationSecreted: P08709 P08709
Total number of polymer chains2
Total formula weight34802.30
Authors
Kemball-Cook, G.,Johnson, D.J.D.,Tuddenham, E.G.D.,Harlos, K. (deposition date: 1999-08-24, release date: 1999-08-31, Last modification date: 2013-02-27)
Primary citationKemball-Cook, G.,Johnson, D.J.,Tuddenham, E.G.,Harlos, K.
Crystal structure of active site-inhibited human coagulation factor VIIa (des-Gla).
J.Struct.Biol., 127:213-223, 1999
Cited by
PubMed: 10544046
DOI: 10.1006/jsbi.1999.4158
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.28 Å)
Structure validation

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon