1CUL

COMPLEX OF GS-ALPHA WITH THE CATALYTIC DOMAINS OF MAMMALIAN ADENYLYL CYCLASE: COMPLEX WITH 2',5'-DIDEOXY-ADENOSINE 3'-TRIPHOSPHATE AND MG

Summary for 1CUL

• Entry DOI: 10.2210/pdb1cul/pdb
• Related: 1CS4
• Descriptor: TYPE V ADENYLYL CYCLASE, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, TYPE II ADENYLYL CYCLASE, ... (11 entities in total)
• Functional Keywords: complex (lyase-hydrolase), hydrolase, signal transducing protein, cyclase, effector enzyme, lyase-hydrolase complex, lyase/lyase/signaling protein, lyase-lyase-signaling protein complex
• Biological source: Canis lupus familiaris (dog); More
• Cellular location: Membrane; Multi-pass membrane protein: P30803 P26769; Cell membrane; Lipid-anchor (By similarity): P04896
• Total number of polymer chains: 3
• Total formula weight: 94123.15

Authors

Tesmer, J.J.G.,Dessauer, C.A.,Sunahara, R.K.,Johnson, R.A.,Gilman, A.G.,Sprang, S.R. (deposition date: 1999-08-20, release date: 2001-01-10, Last modification date: 2024-02-07)

• Primary citation: Tesmer, J.J.,Dessauer, C.W.,Sunahara, R.K.,Murray, L.D.,Johnson, R.A.,Gilman, A.G.,Sprang, S.R.; Molecular basis for P-site inhibition of adenylyl cyclase.; Biochemistry, 39:14464-14471, 2000; PubMed: 11087399; DOI: 10.1021/bi0015562

Experimental method

X-RAY DIFFRACTION (2.4 Å)