1CJU

COMPLEX OF GS-ALPHA WITH THE CATALYTIC DOMAINS OF MAMMALIAN ADENYLYL CYCLASE: COMPLEX WITH BETA-L-2',3'-DIDEOXYATP AND MG

Summary for 1CJU

Entry DOI	10.2210/pdb1cju/pdb
Descriptor	ADENYLATE CYCLASE, TYPE V, ADENYLATE CYCLASE, TYPE II, GUANINE NUCLEOTIDE-BINDING PROTEIN G(S), ... (9 entities in total)
Functional Keywords	complex (lyase-hydrolase), hydrolase, signal transducing protein, cyclase, effector enzyme, lyase-lyase-signaling protein complex, lyase/lyase/signaling protein
Biological source	Canis lupus (dog) More
Cellular location	Membrane; Multi-pass membrane protein: P30803 P26769 Cell membrane; Lipid-anchor (By similarity): P04896
Total number of polymer chains	3
Total formula weight	96402.13
Authors	Tesmer, J.J.G.,Sprang, S.R. (deposition date: 1999-04-16, release date: 1999-08-31, Last modification date: 2023-08-02)
Primary citation	Tesmer, J.J.,Sunahara, R.K.,Johnson, R.A.,Gosselin, G.,Gilman, A.G.,Sprang, S.R. Two-metal-Ion catalysis in adenylyl cyclase. Science, 285:756-760, 1999 Cited by PubMed: 10427002 DOI: 10.1126/science.285.5428.756 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation