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1BL6

THE COMPLEX STRUCTURE OF THE MAP KINASE P38/SB216995

Summary for 1BL6
Entry DOI10.2210/pdb1bl6/pdb
DescriptorPROTEIN (MAP KINASE P38), 4-(4-FLUOROPHENYL)-1-CYCLOROPROPYLMETHYL-5-(4-PYRIDYL)-IMIDAZOLE (3 entities in total)
Functional Keywordstransferase, inhibitors, map kinase, serine/ threonine-protein kinase, p38
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm (By similarity): Q16539
Total number of polymer chains1
Total formula weight43676.69
Authors
Wang, Z.,Canagarajah, B.J.,Boehm, J.C.,Kassis, S.,Cobb, M.H.,Young, P.R.,Abdel-Meguid, S.,Adams, J.L.,Goldsmith, E.J. (deposition date: 1998-07-11, release date: 1999-07-26, Last modification date: 2023-12-27)
Primary citationWang, Z.,Canagarajah, B.J.,Boehm, J.C.,Kassisa, S.,Cobb, M.H.,Young, P.R.,Abdel-Meguid, S.,Adams, J.L.,Goldsmith, E.J.
Structural basis of inhibitor selectivity in MAP kinases.
Structure, 6:1117-1128, 1998
Cited by
PubMed: 9753691
DOI: 10.1016/S0969-2126(98)00113-0
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.5 Å)
Structure validation

217705

數據於2024-03-27公開中

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