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1AY6

THROMBIN INHIBITOR FROM THEONALLA, CYCLOTHEANAMIDE-BASED MACROCYCLIC TRIPEPTIDE MOTIF

Summary for 1AY6
Entry DOI10.2210/pdb1ay6/pdb
Related PRD IDPRD_000410
DescriptorTHROMBIN LIGHT CHAIN, THROMBIN HEAVY CHAIN, HIRUGEN, ... (5 entities in total)
Functional Keywordscomplex of serine protease-inhibitor, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceHomo sapiens (human)
More
Cellular locationSecreted, extracellular space: P00734 P00734
Secreted: P01050
Total number of polymer chains3
Total formula weight36098.17
Authors
Ganesh, V.,Maryanoff, B.E.,Tulinsky, A. (deposition date: 1997-11-14, release date: 1998-03-18, Last modification date: 2023-08-02)
Primary citationGreco, M.N.,Powell, E.T.,Hecker, L.R.,Andrade-Gordon, P.,Kauffman, J.A.,Lewis, J.M.,Ganesh, V.,Tulinsky, A.,Maryanoff, B.E.
Novel thrombin inhibitors that are based on a macrocyclic tripeptide motif
Bioorg.Med.Chem.Lett., 6:2947-2952, 1996
Cited by
PubMed: 8367461
DOI: 10.1016/S0960-894X(96)00554-9
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.8 Å)
Structure validation

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