1AXA
ACTIVE-SITE MOBILITY IN HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 PROTEASE AS DEMONSTRATED BY CRYSTAL STRUCTURE OF A28S MUTANT
1AXA の概要
エントリーDOI | 10.2210/pdb1axa/pdb |
分子名称 | HIV-1 PROTEASE, N-[[1-[N-ACETAMIDYL]-[1-CYCLOHEXYLMETHYL-2-HYDROXY-4-ISOPROPYL]-BUT-4-YL]-CARBONYL]-GLUTAMINYL-ARGINYL-AMIDE (3 entities in total) |
機能のキーワード | hiv protease, mutant, aspartic protease, hydrolase, acid proteinase, aspartyl protease |
由来する生物種 | Human immunodeficiency virus 1 |
タンパク質・核酸の鎖数 | 2 |
化学式量合計 | 22833.04 |
構造登録者 | Hong, L.,Hartsuck, J.A.,Foundling, S.,Ermolieff, J.,Tang, J. (登録日: 1997-10-13, 公開日: 1998-04-15, 最終更新日: 2024-02-07) |
主引用文献 | Hong, L.,Hartsuck, J.A.,Foundling, S.,Ermolieff, J.,Tang, J. Active-site mobility in human immunodeficiency virus, type 1, protease as demonstrated by crystal structure of A28S mutant. Protein Sci., 7:300-305, 1998 Cited by PubMed: 9521105主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (2 Å) |
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