1AQ1

HUMAN CYCLIN DEPENDENT KINASE 2 COMPLEXED WITH THE INHIBITOR STAUROSPORINE

1AQ1 の概要

• エントリーDOI: 10.2210/pdb1aq1/pdb
• 分子名称: CYCLIN-DEPENDENT PROTEIN KINASE 2, STAUROSPORINE (3 entities in total)
• 機能のキーワード: protein kinase, cell cycle, phosphorylation, staurosporine, cell division, mitosis, inhibition
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 34443.02

構造登録者

Endicott, J.A.,Noble, M.E.M.,Johnson, L.N.,Lawrie, A.,Tunnah, P.,Brown, N.R. (登録日: 1997-08-05, 公開日: 1997-11-12, 最終更新日: 2023-08-02)

• 主引用文献: Lawrie, A.M.,Noble, M.E.,Tunnah, P.,Brown, N.R.,Johnson, L.N.,Endicott, J.A.; Protein kinase inhibition by staurosporine revealed in details of the molecular interaction with CDK2.; Nat.Struct.Biol., 4:796-801, 1997; PubMed: 9334743; DOI: 10.1038/nsb1097-796

実験手法

X-RAY DIFFRACTION (2 Å)