1AI1

HIV-1 V3 LOOP MIMIC

Summary for 1AI1

Entry DOI	10.2210/pdb1ai1/pdb
Descriptor	IGG1-KAPPA 59.1 FAB (LIGHT CHAIN), IGG1-KAPPA 59.1 FAB (HEAVY CHAIN), AIB142 (3 entities in total)
Functional Keywords	complex (antibody-peptide), antibody, constrained hiv-1 v3 loop peptide, immunoglobulin, complex (antibody-peptide) complex, complex (antibody/peptide)
Biological source	Mus musculus (house mouse) More
Cellular location	Isoform Secreted: Secreted: P01868 Transmembrane protein gp41: Virion membrane; Single-pass type I membrane protein. Surface protein gp120: Virion membrane; Peripheral membrane protein: P05877
Total number of polymer chains	3
Total formula weight	50711.86
Authors	Ghiara, J.B.,Wilson, I.A. (deposition date: 1996-11-06, release date: 1997-05-15, Last modification date: 2023-08-02)
Primary citation	Ghiara, J.B.,Ferguson, D.C.,Satterthwait, A.C.,Dyson, H.J.,Wilson, I.A. Structure-based design of a constrained peptide mimic of the HIV-1 V3 loop neutralization site. J.Mol.Biol., 266:31-39, 1997 Cited by PubMed: 9054968 DOI: 10.1006/jmbi.1996.0768 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation