1AE4

ALDEHYDE REDUCTASE COMPLEXED WITH COFACTOR AND INHIBITOR, ALPHA CARBON ATOMS ONLY

Summary for 1AE4

Entry DOI	10.2210/pdb1ae4/pdb
Descriptor	ALDEHYDE REDUCTASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, TOLRESTAT (3 entities in total)
Functional Keywords	aldo-keto reductase, oxidoreductase, tim-barrel
Biological source	Sus scrofa (pig)
Total number of polymer chains	1
Total formula weight	37684.64
Authors	El-Kabbani, O. (deposition date: 1997-03-05, release date: 1998-03-11, Last modification date: 2024-04-03)
Primary citation	el-Kabbani, O.,Carper, D.A.,McGowan, M.H.,Devedjiev, Y.,Rees-Milton, K.J.,Flynn, T.G. Studies on the inhibitor-binding site of porcine aldehyde reductase: crystal structure of the holoenzyme-inhibitor ternary complex. Proteins, 29:186-192, 1997 Cited by PubMed: 9329083 DOI: 10.1002/(SICI)1097-0134(199710)29:2<186::AID-PROT6>3.0.CO;2-B PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation