1A7C

HUMAN PLASMINOGEN ACTIVATOR INHIBITOR TYPE-1 IN COMPLEX WITH A PENTAPEPTIDE

Summary for 1A7C

Entry DOI	10.2210/pdb1a7c/pdb
Descriptor	PLASMINOGEN ACTIVATOR INHIBITOR TYPE 1, PENTAPEPTIDE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-D-ribopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
Functional Keywords	serine protease inhibitor, pai-1, carbohydrate, inhibitor complex, protease inhibitor-peptide complex, hydrolase inhibitor-peptide complex, hydrolase inhibitor/peptide
Biological source	Homo sapiens (human)
Total number of polymer chains	3
Total formula weight	44629.88
Authors	Xue, Y.,Inghardt, T.,Sjolin, L.,Deinum, J. (deposition date: 1998-03-12, release date: 1999-03-23, Last modification date: 2020-07-29)
Primary citation	Xue, Y.,Bjorquist, P.,Inghardt, T.,Linschoten, M.,Musil, D.,Sjolin, L.,Deinum, J. Interfering with the inhibitory mechanism of serpins: crystal structure of a complex formed between cleaved plasminogen activator inhibitor type 1 and a reactive-centre loop peptide Structure, 6:627-636, 1998 Cited by PubMed: 9634700 DOI: 10.1016/S0969-2126(98)00064-1 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.95 Å)

Structure validation