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1ZZP

Solution structure of the F-actin binding domain of Bcr-Abl/c-Abl

Summary for 1ZZP
Entry DOI10.2210/pdb1zzp/pdb
NMR InformationBMRB: 6570
DescriptorProto-oncogene tyrosine-protein kinase ABL1 (1 entity in total)
Functional Keywordsfour helix bundle, nuclear export signal, transferase
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm, cytoskeleton. Isoform IB: Nucleus membrane; Lipid-anchor: P00519
Total number of polymer chains1
Total formula weight14150.12
Authors
Hantschel, O.,Wiesner, S.,Guttler, T.,Mackereth, C.D.,Rix, L.L.R.,Mikes, Z.,Dehne, J.,Gorlich, D.,Sattler, M.,Superti-Furga, G. (deposition date: 2005-06-14, release date: 2005-08-30, Last modification date: 2022-03-09)
Primary citationHantschel, O.,Wiesner, S.,Guttler, T.,Mackereth, C.D.,Rix, L.L.R.,Mikes, Z.,Dehne, J.,Gorlich, D.,Sattler, M.,Superti-Furga, G.
Structural Basis for the Cytoskeletal Association of Bcr-Abl/c-Abl.
Mol.Cell, 19:461-473, 2005
Cited by
PubMed: 16109371
DOI: 10.1016/j.molcel.2005.06.030
PDB entries with the same primary citation
Experimental method
SOLUTION NMR
Structure validation

217705

건을2024-03-27부터공개중

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