1ZLT

Crystal Structure of Chk1 Complexed with a Hymenaldisine Analog

Summary for 1ZLT

• Entry DOI: 10.2210/pdb1zlt/pdb
• Descriptor: Serine/threonine-protein kinase Chk1, SULFATE ION, (4Z)-4-(2-AMINO-5-OXO-3,5-DIHYDRO-4H-IMIDAZOL-4-YLIDENE)-2,3-DICHLORO-4,5,6,7-TETRAHYDROPYRROLO[2,3-C]AZEPIN-8(1H)-ONE, ... (4 entities in total)
• Functional Keywords: kinase, transferase
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus: O14757
• Total number of polymer chains: 1
• Total formula weight: 34282.05

Authors

Lee, C.C.,Ng, K.,Wan, Y.,Gray, N.,Spraggon, G. (deposition date: 2005-05-09, release date: 2006-06-27, Last modification date: 2023-08-23)

• Primary citation: Lee, C.C.,Ng, K.,Wan, Y.,Gray, N.,Spraggon, G.; Crystal Structure of Chk1 Complexed with a Hymenaldisine Analog; To be Published,

Experimental method

X-RAY DIFFRACTION (1.74 Å)