1ZGY

Structural and Biochemical Basis for Selective Repression of the Orphan Nuclear Receptor LRH-1 by SHP

Summary for 1ZGY

• Entry DOI: 10.2210/pdb1zgy/pdb
• Descriptor: Peroxisome proliferator activated receptor gamma, Nuclear receptor subfamily 0, group B, member 2, 2,4-THIAZOLIDIINEDIONE, 5-[[4-[2-(METHYL-2-PYRIDINYLAMINO)ETHOXY]PHENYL]METHYL]-(9CL), ... (4 entities in total)
• Functional Keywords: protein-peptide complex, transcription
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus: P37231; Cytoplasm : P97947
• Total number of polymer chains: 2
• Total formula weight: 33301.76

Authors

Li, Y.,Choi, M.,Suino, K.,Kovach, A.,Daugherty, J.,Kliewer, S.A.,Xu, H.E. (deposition date: 2005-04-22, release date: 2005-07-26, Last modification date: 2023-08-23)

• Primary citation: Li, Y.,Choi, M.,Suino, K.,Kovach, A.,Daugherty, J.,Kliewer, S.A.,Xu, H.E.; Structural and biochemical basis for selective repression of the orphan nuclear receptor liver receptor homolog 1 by small heterodimer partner.; Proc.Natl.Acad.Sci.Usa, 102:9505-9510, 2005; PubMed: 15976031; DOI: 10.1073/pnas.0501204102

Experimental method

X-RAY DIFFRACTION (1.8 Å)