1Z68
Crystal Structure Of Human Fibroblast Activation Protein alpha
Summary for 1Z68
Entry DOI | 10.2210/pdb1z68/pdb |
Descriptor | fibroblast activation protein, alpha subunit, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total) |
Functional Keywords | seprase, fibroblast activation protein alpha, fapalpha, dipeptidylpeptidase, s9b, integral membrane serine protease, lyase |
Biological source | Homo sapiens (human) |
Cellular location | Cell membrane; Single-pass type II membrane protein: Q12884 |
Total number of polymer chains | 2 |
Total formula weight | 169170.11 |
Authors | Aertgeerts, K.,Levin, I.,Shi, L.,Prasad, G.S.,Zhang, Y.,Kraus, M.L.,Salakian, S.,Snell, G.P.,Sridhar, V.,Wijnands, R.,Tennant, M.G. (deposition date: 2005-03-21, release date: 2005-04-12, Last modification date: 2023-08-23) |
Primary citation | Aertgeerts, K.,Levin, I.,Shi, L.,Snell, G.P.,Jennings, A.,Prasad, G.S.,Zhang, Y.,Kraus, M.L.,Salakian, S.,Sridhar, V.,Wijnands, R.,Tennant, M.G. Structural and kinetic analysis of the substrate specificity of human fibroblast activation protein alpha. J.Biol.Chem., 280:19441-19444, 2005 Cited by PubMed: 15809306DOI: 10.1074/jbc.C500092200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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