1Y86

Crystal structure of the A-DNA GCGTAT*CGC with a 2'-O-[2-(fluoro)ethyl] Thymidine (T*)

Summary for 1Y86

• Entry DOI: 10.2210/pdb1y86/pdb
• Related: 1Y7F 1Y84
• Descriptor: 5'-D(*GP*CP*GP*TP*AP*(125)P*AP*CP*GP*C)-3' (2 entities in total)
• Functional Keywords: a-dna, o2'-modification, decamer, dna
• Total number of polymer chains: 2
• Total formula weight: 6214.10

Authors

Egli, M.,Minasov, G.,Tereshko, V.,Pallan, P.S.,Teplova, M.,Inamati, G.B.,Lesnik, E.A.,Owens, S.R.,Ross, B.S.,Prakash, T.P.,Manoharan, M. (deposition date: 2004-12-10, release date: 2005-06-28, Last modification date: 2023-08-23)

• Primary citation: Egli, M.,Minasov, G.,Tereshko, V.,Pallan, P.S.,Teplova, M.,Inamati, G.B.,Lesnik, E.A.,Owens, S.R.,Ross, B.S.,Prakash, T.P.,Manoharan, M.; Probing the Influence of Stereoelectronic Effects on the Biophysical Properties of Oligonucleotides: Comprehensive Analysis of the RNA Affinity, Nuclease Resistance, and Crystal Structure of Ten 2'-O-Ribonucleic Acid Modifications.; Biochemistry, 44:9045-9057, 2005; PubMed: 15966728; DOI: 10.1021/bi050574m

Experimental method

X-RAY DIFFRACTION (1.7 Å)