1Y75
A new form of catalytically inactive phospholipase A2 with an unusual disulphide bridge Cys 32- Cys 49 reveals recognition for N-acetylglucosmine
Summary for 1Y75
Entry DOI | 10.2210/pdb1y75/pdb |
Related | 1S6B |
Descriptor | phospholipase A2 isoform 5, phospholipase A2 isoform 6, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total) |
Functional Keywords | enzyme, activity, molecular association, hydrolase |
Biological source | Naja sagittifera More |
Cellular location | Secreted: Q5G291 Q5G290 |
Total number of polymer chains | 2 |
Total formula weight | 26139.60 |
Authors | Jabeen, T.,Singh, N.,Jasti, J.,Singh, R.K.,Sharma, S.,Perbandt, M.,Betzel, C.,Kaur, P.,Srinivasan, A.,Singh, T.P. (deposition date: 2004-12-08, release date: 2005-05-03, Last modification date: 2020-07-29) |
Primary citation | Jabeen, T.,Singh, N.,Singh, R.K.,Jasti, J.,Sharma, S.,Kaur, P.,Srinivasan, A.,Singh, T.P. Crystal structure of a heterodimer of phospholipase A2 from Naja naja sagittifera at 2.3 A resolution reveals the presence of a new PLA2-like protein with a novel cys 32-Cys 49 disulphide bridge with a bound sugar at the substrate-binding site Proteins, 62:329-337, 2006 Cited by PubMed: 16287060DOI: 10.1002/prot.20708 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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