1XQZ
Crystal Structure of hPim-1 kinase at 2.1 A resolution
Summary for 1XQZ
Entry DOI | 10.2210/pdb1xqz/pdb |
Related | 1xr1 |
Descriptor | Proto-oncogene serine/threonine-protein kinase Pim-1 (2 entities in total) |
Functional Keywords | protein kinase fold, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Isoform 2: Cytoplasm. Isoform 1: Cell membrane: P11309 |
Total number of polymer chains | 1 |
Total formula weight | 34251.91 |
Authors | Qian, K.C.,Wang, L.,Hickey, E.R.,Studts, J.,Barringer, K.,Peng, C.,Kronkaitis, A.,Li, J.,White, A.,Mische, S.,Farmer, B. (deposition date: 2004-10-13, release date: 2004-11-09, Last modification date: 2024-02-14) |
Primary citation | Qian, K.C.,Wang, L.,Hickey, E.R.,Studts, J.,Barringer, K.,Peng, C.,Kronkaitis, A.,Li, J.,White, A.,Mische, S.,Farmer, B. Structural Basis of Constitutive Activity and a Unique Nucleotide Binding Mode of Human Pim-1 Kinase. J.Biol.Chem., 280:6130-6137, 2005 Cited by PubMed: 15525646DOI: 10.1074/jbc.M409123200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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