1UY9

Human Hsp90-alpha with 8-Benzo[1,3]dioxol-,5-ylmethyl-9-butyl-9H-purin-6-ylamine

Summary for 1UY9

Entry DOI	10.2210/pdb1uy9/pdb
Related	1BYQ 1OSF 1UY6 1UY7 1UY8 1UYC 1UYD 1UYE 1UYF 1UYG 1UYH 1UYI 1UYK 1UYL 1UYM 1YER 1YES 1YET
Descriptor	HEAT SHOCK PROTEIN HSP 90-ALPHA, 8-BENZO[1,3]DIOXOL-,5-YLMETHYL-9-BUTYL-9H- (3 entities in total)
Functional Keywords	hsp90, atpase, pu6, chaperone, atp-binding, heat shock
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Cytoplasm : P07900
Total number of polymer chains	1
Total formula weight	26927.14
Authors	Wright, L.,Barril, X.,Dymock, B.,Sheridan, L.,Surgenor, A.,Beswick, M.,Drysdale, M.,Collier, A.,Massey, A.,Davies, N.,Fink, A.,Fromont, C.,Aherne, W.,Boxall, K.,Sharp, S.,Workman, P.,Hubbard, R.E. (deposition date: 2004-03-02, release date: 2004-07-01, Last modification date: 2023-12-13)
Primary citation	Wright, L.,Barril, X.,Dymock, B.,Sheridan, L.,Surgenor, A.,Beswick, M.,Drysdale, M.,Collier, A.,Massey, A.,Davies, N.,Fink, A.,Fromont, C.,Aherne, W.,Boxall, K.,Sharp, S.,Workman, P.,Hubbard, R.E. Structure-Activity Relationships in Purine-Based Inhibitor Binding to Hsp90 Isoforms Chem.Biol., 11:775-, 2004 Cited by PubMed: 15217611 DOI: 10.1016/J.CHEMBIOL.2004.03.033 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation