1SMH

Protein kinase A variant complex with completely ordered N-terminal helix

1SMH の概要

• エントリーDOI: 10.2210/pdb1smh/pdb
• 分子名称: cAMP-Dependent Protein Kinase, alpha-catalytic subunit, cAMP-dependent protein kinase inhibitor, alpha form, (R,R)-2,3-BUTANEDIOL, ... (5 entities in total)
• 機能のキーワード: pka; protein kinase a; camp-dependent protein kinase; phosphorylation; ser10; myristoylation; posttranslational modification; signaling; membrane, alpha helix, signaling protein, transferase-inhibitor complex, transferase/inhibitor
• 由来する生物種: Bos taurus (cattle); 詳細
• 細胞内の位置: Cytoplasm: P00517
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 43751.92

構造登録者

Breitenlechner, C.,Engh, R.A.,Huber, R.,Kinzel, V.,Bossemeyer, D.,Gassel, M. (登録日: 2004-03-09, 公開日: 2004-07-06, 最終更新日: 2021-10-27)

• 主引用文献: Breitenlechner, C.,Engh, R.A.,Huber, R.,Kinzel, V.,Bossemeyer, D.,Gassel, M.; The Typically Disordered N-Terminus of PKA Can Fold as a Helix and Project the Myristoylation Site into Solution; Biochemistry, 43:7743-7749, 2004; PubMed: 15196017; DOI: 10.1021/bi0362525

実験手法

X-RAY DIFFRACTION (2.044 Å)