1S9Y

Crystal Structure Analysis of NY-ESO-1 epitope analogue, SLLMWITQS, in complex with HLA-A2

Summary for 1S9Y

Entry DOI	10.2210/pdb1s9y/pdb
Related	1S9W 1S9X
Descriptor	HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, NY-ESO-1 peptide analogue S9S, ... (5 entities in total)
Functional Keywords	immune system
Biological source	Homo sapiens (human) More
Cellular location	Membrane; Single-pass type I membrane protein: P01892 Secreted: P61769
Total number of polymer chains	3
Total formula weight	44778.79
Authors	Webb, A.I.,Dunstone, M.A.,Chen, W.,Aguilar, M.I.,Chen, Q.,Chang, L.,Kjer-Nielsen, L.,Beddoe, T.,McCluskey, J.,Rossjohn, J.,Purcell, A.W. (deposition date: 2004-02-05, release date: 2004-09-28, Last modification date: 2011-07-13)
Primary citation	Webb, A.I.,Dunstone, M.A.,Chen, W.,Aguilar, M.I.,Chen, Q.,Jackson, H.,Chang, L.,Kjer-Nielsen, L.,Beddoe, T.,McCluskey, J.,Rossjohn, J.,Purcell, A.W. Functional and structural characteristics of NY-ESO-1-related HLA A2-restricted epitopes and the design of a novel immunogenic analogue J.Biol.Chem., 279:23438-23446, 2004 Cited by PubMed: 15004033 DOI: 10.1074/jbc.M314066200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation