1S8D

Structural basis for degenerate recognition of HIV peptide variants by cytotoxic lymphocyte, variant SL9-3A

Summary for 1S8D

Entry DOI	10.2210/pdb1s8d/pdb
Descriptor	HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, gag peptide, ... (4 entities in total)
Functional Keywords	ctl, cytotoxic t lymphocytes, hiv, human immunodeficiency virus, mhc, major histocompatibility complex, pmhc, peptide-mhc complex, rmsd, root-mean-squared deviation, siv, simian immunodeficiency virus, tcr, t-cell receptor, immune system
Biological source	Homo sapiens (human) More
Cellular location	Membrane; Single-pass type I membrane protein: Q9TQH5 Secreted: P01884
Total number of polymer chains	3
Total formula weight	44491.37
Authors	Martinez-Hackert, E.,Anikeeva, N.,Kalams, S.A.,Walker, B.D.,Hendrickson, W.A.,Sykulev, Y. (deposition date: 2004-02-02, release date: 2005-09-06, Last modification date: 2023-08-23)
Primary citation	Martinez-Hackert, E.,Anikeeva, N.,Kalams, S.A.,Walker, B.D.,Hendrickson, W.A.,Sykulev, Y. Structural Basis for Degenerate Recognition of Natural HIV Peptide Variants by Cytotoxic Lymphocytes. J.Biol.Chem., 281:20205-20212, 2006 Cited by PubMed: 16702212 DOI: 10.1074/jbc.M601934200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation