1PY4

Beta2 microglobulin mutant H31Y displays hints for amyloid formations

Summary for 1PY4

Entry DOI	10.2210/pdb1py4/pdb
Descriptor	Beta-2-microglobulin precursor (2 entities in total)
Functional Keywords	amyloid, dialysis related amyloidosis, c-type immunoglobulin, protein mutant, signaling protein
Biological source	Homo sapiens (human)
Cellular location	Secreted: P61769
Total number of polymer chains	4
Total formula weight	47617.53
Authors	Rosano, C.,Zuccotti, S.,Mangione, P.,Giorgetti, S.,Bellotti, V.,Pettirossi, F.,Corazza, A.,Viglino, P.,Esposito, G.,Bolognesi, M. (deposition date: 2003-07-08, release date: 2004-05-04, Last modification date: 2023-08-16)
Primary citation	Rosano, C.,Zuccotti, S.,Mangione, P.,Giorgetti, S.,Bellotti, V.,Pettirossi, F.,Corazza, A.,Viglino, P.,Esposito, G.,Bolognesi, M. beta2-microglobulin H31Y variant 3D structure highlights the protein natural propensity towards intermolecular aggregation J.Mol.Biol., 335:1051-1064, 2004 Cited by PubMed: 14698299 DOI: 10.1016/j.jmb.2003.11.040 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation