1PW2

APO STRUCTURE OF HUMAN CYCLIN-DEPENDENT KINASE 2

1PW2 の概要

• エントリーDOI: 10.2210/pdb1pw2/pdb
• 関連するPDBエントリー: 1AQ1 1B39 1CKP 1DI8 1DM2 1E1V 1E1X 1E9H 1FIN 1FVT 1FVV 1G5S 1GIH 1GZ8 1HCK 1HCL 1JSV 1JVP 1KE5 1KE6 1KE7 1KE8 1KE9
• 分子名称: Cell division protein kinase 2 (2 entities in total)
• 機能のキーワード: protein kinase, cell cycle, phosphorylation, cell division, mitosis, inhibition, transferase, serine/threonine-protein kinase, atp-binding, 3d-structure.
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 33976.49

構造登録者

Wu, S.Y.,McNae, I.,Kontopidis, G.,McClue, S.J.,McInnes, C.,Stewart, K.J.,Wang, S.,Zheleva, D.I.,Marriage, H.,Lane, D.P.,Taylor, P.,Fischer, P.M.,Walkinshaw, M.D. (登録日: 2003-06-30, 公開日: 2003-12-09, 最終更新日: 2023-08-16)

• 主引用文献: Wu, S.Y.,McNae, I.,Kontopidis, G.,McClue, S.J.,McInnes, C.,Stewart, K.J.,Wang, S.,Zheleva, D.I.,Marriage, H.,Lane, D.P.,Taylor, P.,Fischer, P.M.,Walkinshaw, M.D.; Discovery of a novel family of CDK inhibitors with the program LIDAEUS: structural basis for ligand-induced disordering of the activation loop.; Structure, 11:399-410, 2003; PubMed: 12679018; DOI: 10.1016/S0969-2126(03)00060-1

実験手法

X-RAY DIFFRACTION (1.95 Å)